A natural extract derived from the neem tree, commonly found in India, could potentially be used to treat pancreatic cancer without harming normal, healthy cells, a new study has claimed.
Scientists tested nimbolide, a compound found in neem leaves, against pancreatic cancer in cell lines and mice. The results showed that nimbolide can stop pancreatic cancer’s growth and metastasis without harming normal, healthy cells.
Researchers observed that nimbolide was able to reduce the migration and invasion capabilities of pancreatic cancer cells by 70%; meaning the cancerous cells did not become aggressive and spread.
According to researchers, that is promising. In humans, this migration and invasion-or metastasis-of pancreatic cancer to other regions of the body is the chief cause of mortality. Nimbolide treatments also induced cancer cell death, causing the size and number of pancreatic cancer cell colonies to drop by 80%.
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